RELEVANCE: There are no FDA approved medications for the treatment of Methamphetamine Use Disorder (MUD). Current treatment options rely heavily on counseling and behavioral interventions. Scientific evidence supports a combination strategy of pharmacotherapy approaches with behavioral therapies to improve patient outcomes and redefine treatment approach for stimulant use disorder.

DESCRIPTION: Clear Scientific has developed CS-1103, the first rationally derived small molecule that has capacity for removing methamphetamine from the body. Funded by a grant from the National Institute on Drug Abuse, this molecule is being tested as an antidote against acute intoxication from methamphetamine.

STATUS: In development